Tg(Tek-cre)1Rwng
Transgene Detail

Summary

• Symbol: Tg(Tek-cre)1Rwng
• Name: transgene insertion 1, Rong Wang
• MGI ID: MGI:3608912
• Synonyms: Tg(Tek-cre)1Lfr, tie2-cre, Tie2Cre
• Transgene: Tg(Tek-cre)1Rwng Location: unknown
• Alliance: Tg(Tek-cre)1Rwng page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tek-cre)1Rwng expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Tek

• Mutation details: The endothelial specific receptor tyrosine kinase promoter was used to drive expression of cre recombinase. Nine founder lines were produced and one of these was selected for use that efficiently mediated gene excision. Cre was active in the blood islands of extraembryonic mesoderm at E7.5 and in the dorsal aortae at E8.5. By E11.5 it was active in the endothelial cells of all blood vessels. (J:102190, J:104401)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tek (species not specified) Summary of all recombinase alleles driven by Tek. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:102190 Proctor JM, et al., Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci. 2005 Oct 26;25(43):9940-8
• All: 12 reference(s)