Aqp7^tm1.1Suc
Targeted Allele Detail

Summary

• Symbol: Aqp7^tm1.1Suc
• Name: aquaporin 7; targeted mutation 1.1, Shinichi Uchida
• MGI ID: MGI:3608967
• Synonyms: Aqp7^-
• Gene: Aqp7 Location: Chr4:41033074-41048139 bp, - strand Genetic Position: Chr4, 20.83 cM, cytoband B1
• Alliance: Aqp7^tm1.1Suc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102454
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Cre mediated recombination was used to remove exon 2 of the locus. (J:102454)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aqp7 Mutation: 24 strains or lines available

References

• Original: J:102454 Sohara E, et al., Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice. Am J Physiol Renal Physiol. 2005 Dec;289(6):F1195-200
• All: 5 reference(s)