Epb41l3^tm1Jkis
Targeted Allele Detail

Summary

• Symbol: Epb41l3^tm1Jkis
• Name: erythrocyte membrane protein band 4.1 like 3; targeted mutation 1, Joseph L Kissil
• MGI ID: MGI:3609004
• Synonyms: 4.1B^-
• Gene: Epb41l3 Location: Chr17:69382678-69596984 bp, + strand Genetic Position: Chr17, 40.15 cM
• Alliance: Epb41l3^tm1Jkis page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102380
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced most of the 3' sequence in exon 3, which is the second coding exon of the 4.1B locus and contains the initiating codon of the Dal-1 isoform. Western blot failed to detect protein in mutant mice. (J:102380)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Epb41l3 Mutation: 46 strains or lines available

References

• Original: J:102380 Yi C, et al., Loss of the putative tumor suppressor band 4.1B/Dal1 gene is dispensable for normal development and does not predispose to cancer. Mol Cell Biol. 2005 Nov;25(22):10052-9
• All: 9 reference(s)