Ightm3Tim
Targeted Allele Detail
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| Symbol: |
Ightm3Tim |
| Name: |
immunoglobulin heavy chain complex; targeted mutation 3, Tim Manser |
| MGI ID: |
MGI:3609136 |
| Synonyms: |
HK171 |
| Gene: |
Igh Location: Chr12:113222388-115973574 bp, - strand Genetic Position: Chr12, Syntenic
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| Germline Transmission: |
Earliest citation of germline transmission:
J:102308
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A targeting vector was designed to replace J1 through J4 with a neomycin resistance cassette followed by the 36-65VDJ region with the following amino acid substitutions: A9V, Y32N, I51N, T58I, K59T, S77N, V100E, Y107K, with numbering from the mature amino terminus of the H chain.
(J:102308)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Igh Mutation: |
44 strains or lines available
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| Original: |
J:102308 Heltemes-Harris L, et al., An antibody VH gene that promotes marginal zone B cell development and heavy chain allelic inclusion. Int Immunol. 2005 Nov;17(11):1447-61 |
| All: |
1 reference(s) |
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Analysis Tools
