Mtf1^tm2Wsc
Targeted Allele Detail

Summary

• Symbol: Mtf1^tm2Wsc
• Name: metal response element binding transcription factor 1; targeted mutation 2, Walter Schaffner
• MGI ID: MGI:3609186
• Synonyms: Mtf1^loxP
• Gene: Mtf1 Location: Chr4:124696342-124743593 bp, + strand Genetic Position: Chr4, 57.91 cM, cytoband D1
• Alliance: Mtf1^tm2Wsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102512
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to flank exons 3 and 4, encoding four of the six zinc fingers of the DNA-binding domain, with loxP sites. (J:102512)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtf1 Mutation: 38 strains or lines available

References

• Original: J:102512 Wimmer U, et al., Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. Nucleic Acids Res. 2005;33(18):5715-27
• All: 1 reference(s)