Mmp9^tm1Amr
Targeted Allele Detail

Summary

• Symbol: Mmp9^tm1Amr
• Name: matrix metallopeptidase 9; targeted mutation 1, Anne M Romanic
• MGI ID: MGI:3609228
• Synonyms: Mmp9^-
• Gene: Mmp9 Location: Chr2:164782700-164797770 bp, + strand Genetic Position: Chr2, 85.27 cM, cytoband H1-H2
• Alliance: Mmp9^tm1Amr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The locus was disrupted upon the insertion of a pgk-neo in place of exons 1-12. Western blot of mutant hearts confirmed absence of protein. (J:102541)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mmp9 Mutation: 50 strains or lines available

References

• Original: J:102541 Romanic AM, et al., Myocardial protection from ischemia/reperfusion injury by targeted deletion of matrix metalloproteinase-9. Cardiovasc Res. 2002 Jun;54(3):549-58
• All: 1 reference(s)