Mapk11^tm1Jsca
Targeted Allele Detail

Summary

• Symbol: Mapk11^tm1Jsca
• Name: mitogen-activated protein kinase 11; targeted mutation 1, J Simon C Arthur
• MGI ID: MGI:3609429
• Synonyms: p38beta^-
• Gene: Mapk11 Location: Chr15:89026685-89033809 bp, - strand Genetic Position: Chr15, 44.66 cM, cytoband E3
• Alliance: Mapk11^tm1Jsca page

Developmental defects in Mapk14^tm2Nbr/Mapk14^tm2Nbr Edil3^{Tg(Sox2-cre)1Amc}/0 Mapk11^tm1Jsca/Mapk11^tm1Jsca embryos

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107771
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Intragenic deletion Exons 2-7 were deleted. Immuoblot confirmed ablation of the locus. (J:102857, J:107771)

Generation of the Mapk14^tm3.1(Mapk11)Nbr allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapk11 Mutation: 35 strains or lines available

References

• Original: J:107771 Beardmore VA, et al., Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol Cell Biol. 2005 Dec;25(23):10454-64
• All: 7 reference(s)