Aldh1a1^tm1.1Ngb
Targeted Allele Detail

Summary

• Symbol: Aldh1a1^tm1.1Ngb
• Name: aldehyde dehydrogenase family 1, subfamily A1; targeted mutation 1.1, Norbert B Ghyselinck
• MGI ID: MGI:3609477
• Synonyms: Aldh1a1^L-
• Gene: Aldh1a1 Location: Chr19:20470079-20620829 bp, + strand Genetic Position: Chr19, 13.91 cM
• Alliance: Aldh1a1^tm1.1Ngb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102847
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 8 was deleted via cre-mediated excision. Western blot failed to detect the encoded protein in mutant liver samples. (J:102847)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aldh1a1 Mutation: 39 strains or lines available

References

• Original: J:102847 Matt N, et al., Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. Development. 2005 Nov;132(21):4789-800
• All: 1 reference(s)