Steap3^tm1.1Mdf
Targeted Allele Detail

Summary

• Symbol: Steap3^tm1.1Mdf
• Name: STEAP family member 3; targeted mutation 1.1, Mark D Fleming
• MGI ID: MGI:3609928
• Gene: Steap3 Location: Chr1:120154137-120198810 bp, - strand Genetic Position: Chr1, 52.66 cM, cytoband E2
• Alliance: Steap3^tm1.1Mdf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103440
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Part of intron 1, all of exon 2 and part of intron 2 have been deleted. A single loxP sequence marks the site where the remaining 5' segment of intron 1 and the 3' segment of intron 2 are joined. (J:103440)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Steap3 Mutation: 63 strains or lines available

References

• Original: J:103440 Ohgami RS, et al., Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet. 2005 Nov;37(11):1264-9
• All: 1 reference(s)