Vps26a^tm1Cos
Targeted Allele Detail

Summary

• Symbol: Vps26a^tm1Cos
• Name: VPS26 retromer complex component A; targeted mutation 1, Frank Costantini
• MGI ID: MGI:3610386
• Synonyms: Hbeta58^-
• Gene: Vps26a Location: Chr10:62291014-62322584 bp, - strand Genetic Position: Chr10, 32.41 cM, cytoband B3-B5
• Alliance: Vps26a^tm1Cos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102476
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector was designed to replace exon 2 of the vacuolar protein sorting 26 homolog A gene with a neomycin(neo) resistance cassette and a polyadenylation sequence. (direct communication)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vps26a Mutation: 32 strains or lines available

References

• Original: J:102476 Griffin CT, et al., Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15173-7
• All: 3 reference(s)