Snx2^tm1Mag
Targeted Allele Detail

Summary

• Symbol: Snx2^tm1Mag
• Name: sorting nexin 2; targeted mutation 1, Terry Magnuson
• MGI ID: MGI:3610410
• Synonyms: Snx2^-
• Gene: Snx2 Location: Chr18:53309388-53353937 bp, + strand Genetic Position: Chr18, 28.99 cM, cytoband D1
• Alliance: Snx2^tm1Mag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103556
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding portion of exon 1, encoding amino acids 1-36, and its subsequent splice junction were replaced with a floxed HIS3/neo cassette. Western blot confirmed absence of protein in mutants. (J:103556)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Snx2 Mutation: 43 strains or lines available

References

• Original: J:103556 Schwarz DG, et al., Genetic analysis of sorting nexins 1 and 2 reveals a redundant and essential function in mice. Mol Biol Cell. 2002 Oct;13(10):3588-600
• All: 2 reference(s)