Pax6^ADD4802
Chemically induced Allele Detail

Summary

• Symbol: Pax6^ADD4802
• Name: paired box 6; ADD4802
• MGI ID: MGI:3611067
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^ADD4802 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A G to A transition in intron 8 changes splicing and leads to an altered open reading frame and then to a premature stop codon. (J:103785)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 94 strains or lines available

References

• Original: J:103785 Graw J, et al., Three novel Pax6 alleles in the mouse leading to the same small-eye phenotype caused by different consequences at target promoters. Invest Ophthalmol Vis Sci. 2005 Dec;46(12):4671-83
• All: 1 reference(s)