Pde6a^nmf282
Chemically induced Allele Detail

Summary

• Symbol: Pde6a^nmf282
• Name: phosphodiesterase 6A, cGMP-specific, rod, alpha; neuroscience mutagenesis facility, 282
• MGI ID: MGI:3611307
• Synonyms: nmf-282, NMF282
• Gene: Pde6a Location: Chr18:61353387-61422995 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Pde6a^nmf282 page

Mutation origin

• Strain of Origin: A.B6-Tyr⁺/J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutation was identified in an ENU mutagenesis screen. The molecular mutation is a single nucleotide G to A missense transition in exon 16, predicted to cause an amino acid change from valine to methionine (V685M). (J:142108)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pde6a Mutation: 52 strains or lines available

References

• Original: J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 8 reference(s)