Rv2^BALB/cJ
QTL Variant Detail

Summary

• QTL variant: Rv2^BALB/cJ
• Name: Rauscher leukemia virus susceptibility 2; BALB/cJ
• MGI ID: MGI:3611350
• QTL: Rv2 Location: unknown Genetic Position: Chr9, Syntenic

Variant origin

• Strain of Specimen: BALB/cJ

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers susceptibility to Rauscher leukemia virus compared to C57BL/6 and C57BL/10. (J:7613)

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:7613

Rv-2 is assigned to Chromosome 9 by virtue of its typing in two congenic strains, B6.C-H7^b/By and B10.C-H7^b/(47N)Sn. Both of these strains are congenic for the BALB/cJ alleles at H-7 (59 cM), Mst1r (60 cM; formerly named Fv-2) and Rv-2. The BALB/cJ-derived allele of Rv2 appears to be associated with susceptibility to Rauscher leukemia virus. Additional genetic tests are required to determine whether Rv-2 is identical to Mst1r.

References

• Original: J:7613 Heller E, et al., Chromosomal assignment of two murine genes controlling susceptibility to spleen focus formation by Rauscher leukemia virus. Exp Hematol. 1984 Sep;12(8):645-9
• All: 1 reference(s)