Rasgrf1tm4.1Pds
Targeted Allele Detail
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Symbol: |
Rasgrf1tm4.1Pds |
Name: |
RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 4.1, Paul D Soloway |
MGI ID: |
MGI:3611767 |
Synonyms: |
Flox-R, Rasgrf1tm4Pds |
Gene: |
Rasgrf1 Location: Chr9:89791961-89909030 bp, + strand Genetic Position: Chr9, 47.31 cM
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Alliance: |
Rasgrf1tm4.1Pds page
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Germline Transmission: |
Earliest citation of germline transmission:
J:103751
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A targeting vector was designed to flank the direct repeat sequence downstream of the differentially methylated domain (DMD). A neomycin resistance cassette flanked by a FRT sites that was included downstream of the floxed sequence was removed via FLPe expression.
(J:117666)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rasgrf1 Mutation: |
66 strains or lines available
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Original: |
J:103751 Yoon B, et al., Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Mol Cell Biol. 2005 Dec;25(24):11184-90 |
All: |
3 reference(s) |
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