Del(3Cd1d2-Cd1d1)1Sbp
Targeted Allele Detail

Summary

• Symbol: Del(3Cd1d2-Cd1d1)1Sbp
• Name: deletion, Chr3, Steven P Balk 1; deletion, Chr 3, Steven P Balk 1
• MGI ID: MGI:3611776
• Synonyms: CD1d^-, Cd1d1/Cd1d2^tm1Spb, Cd1d1/Cd1d2^tm1Stst, CD1d KO, CD1d^null, CD1 KO
• Gene: Del(3Cd1d2-Cd1d1)1Sbp Location: unknown Genetic Position: Chr3, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58315
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(3Cd1d2-Cd1d1)1Sbp involves 2 genes/genome features (Cd1d2, Cd1d1) View all
• Mutation details: A genomic region containing Cd1d1 and Cd1d2 genes was replaced with a single neomycin cassette by homologous recombination. (J:106350)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Del(3Cd1d2-Cd1d1)1Sbp Mutation: 2 strains or lines available

References

• Original: J:58315 Sonoda KH, et al., CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site [see comments]. J Exp Med. 1999 Nov 1;190(9):1215-26
• All: 101 reference(s)