Jak3^bfy
Chemically induced Allele Detail

Summary

• Symbol: Jak3^bfy
• Name: Janus kinase 3; buffy
• MGI ID: MGI:3611885
• Gene: Jak3 Location: Chr8:72129027-72143221 bp, + strand Genetic Position: Chr8, 34.43 cM
• Alliance: Jak3^bfy page

Mutation origin

• Strain of Origin: C57BL/6JSfdAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation, which was discovered in an ENU mutagenesis screen, is a T-to-C transition at nucleotide 1214, resulting in replacement of leucine with proline at amino acid position 398 of the protein (L398P).
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Jak3 Mutation: 84 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 1 reference(s)