Stat1^fae
Chemically induced Allele Detail

Summary

• Symbol: Stat1^fae
• Name: signal transducer and activator of transcription 1; face
• MGI ID: MGI:3611892
• Gene: Stat1 Location: Chr1:52158599-52201024 bp, + strand Genetic Position: Chr1, 26.81 cM
• Alliance: Stat1^fae page

Mutation origin

• Strain of Origin: C57BL/6JSfdAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation was discovered in an ENU mutagenesis screen. It causes a T-to-A transversion at nucleotide 2263 of the mRNA, which in turn results in substitution of lysine for methionine at amino acid 654 of the protein (M654K). (J:105311)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Stat1 Mutation: 74 strains or lines available

References

• Original: J:105311 Yates A, et al., Involvement of ENU induced mutant of Stat1 in the immune system. MGI Direct Data Submission. 2006
• All: 1 reference(s)