Prlhr^tm1Map
Targeted Allele Detail

Summary

• Symbol: Prlhr^tm1Map
• Name: prolactin releasing hormone receptor; targeted mutation 1, Marc Parmentier
• MGI ID: MGI:3611903
• Synonyms: Gpr10^-
• Gene: Prlhr Location: Chr19:60455170-60456742 bp, - strand Genetic Position: Chr19, 56.52 cM
• Alliance: Prlhr^tm1Map page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103932
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A tau-lacZ fusion gene and a TK-neo cassette replaced the first 194 codons, sequence encoding transmembrane segments 1-4. Transcripts were not detected by RT-PCR in mutant mice. (J:103932)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prlhr Mutation: 17 strains or lines available

References

• Original: J:103932 Laurent P, et al., The prolactin-releasing peptide antagonizes the opioid system through its receptor GPR10. Nat Neurosci. 2005 Dec;8(12):1735-41
• All: 1 reference(s)