Summary |
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Variant origin |
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Variant description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:6736Linkage analysis was performed on a population of (NZB/BlN x B10.D2/oSnJ)F1 x B10.D2/oSnJ backcross animals to map loci affecting cytotoxic T lymphocyte (CTL) response to H2-compatible cells. Parental strain NZB/BlN exhibits increased in vitro CTL response to H2-compatible cells. Ctl1 (cytotoxic T lymphocyte response 1) showed linkage to mouse Chromosome 1 near Ly9 (93.9 cM). Animals heterozygous for NZB/BlN-derived alleles at Ctl1 exhibit stronger CTL response compared to animals homozygous for B10.D2/oSnJ-derived alleles. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/22/2024 MGI 6.24 |
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