Ptafr^tm1Eit
Targeted Allele Detail

Summary

• Symbol: Ptafr^tm1Eit
• Name: platelet-activating factor receptor; targeted mutation 1, Elaine I Tuomanen
• MGI ID: MGI:3612592
• Synonyms: PAFr^-
• Gene: Ptafr Location: Chr4:132291378-132309994 bp, + strand Genetic Position: Chr4, 65.56 cM, cytoband D2.2
• Alliance: Ptafr^tm1Eit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104293
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A TK-neo cassette was inserted to delete 951 of 1,023 bp of the coding sequence. (J:104293)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptafr Mutation: 22 strains or lines available

References

• Original: J:104293 Radin JN, et al., beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae. Infect Immun. 2005 Dec;73(12):7827-35
• All: 6 reference(s)