Wnt3a^tm1(cre)Eag
Targeted Allele Detail

Summary

• Symbol: Wnt3a^tm1(cre)Eag
• Name: wingless-type MMTV integration site family, member 3A; targeted mutation 1, Elizabeth A Grove
• MGI ID: MGI:3612795
• Synonyms: Wnt3a-Cre, Wnt3a-IRES-Cre
• Gene: Wnt3a Location: Chr11:59138859-59181578 bp, - strand Genetic Position: Chr11, 37.17 cM
• Alliance: Wnt3a^tm1(cre)Eag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104373
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Wnt3a^tm1(cre)Eag expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wnt3a (MGI:98956)

• Mutation details: An IRES-cre was inserted into the 3' end of the locus via homologous recombination. Endogenous protein was expressed with cre, without disruption, in the hem of coronal sections through E12.5 forebrains. (J:104373)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt3a (mouse) Summary of all recombinase alleles driven by Wnt3a. Alliance mouse Wnt3a gene page

Expression

In Mice Carrying this Mutation:

4 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt3a Mutation: 26 strains or lines available

References

• Original: J:104373 Yoshida M, et al., Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order. Development. 2006 Feb;133(3):537-45
• All: 14 reference(s)