Fgf8^tm2Mrt
Targeted Allele Detail

Summary

• Symbol: Fgf8^tm2Mrt
• Name: fibroblast growth factor 8; targeted mutation 2, Gail R Martin
• MGI ID: MGI:3612999
• Synonyms: Fgf8^lacZ
• Gene: Fgf8 Location: Chr19:45725237-45731354 bp, - strand Genetic Position: Chr19, 38.75 cM, cytoband C3-D
• Alliance: Fgf8^tm2Mrt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101176
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• The allele has the beta-galactosidase sequence inserted into the Fgf8 gene.

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf8 Mutation: 21 strains or lines available

References

• Original: J:101176 Grieshammer U, et al., FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57
• All: 13 reference(s)