Abi1^tm1Pen
Targeted Allele Detail

Summary

• Symbol: Abi1^tm1Pen
• Name: abl interactor 1; targeted mutation 1, Ann Marie Pendergast
• MGI ID: MGI:3613611
• Synonyms: abi1^-
• Gene: Abi1 Location: Chr2:22830085-22930207 bp, - strand Genetic Position: Chr2, 15.18 cM
• Alliance: Abi1^tm1Pen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104623
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:169009)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abi1 Mutation: 78 strains or lines available

References

• Original: J:104623 Zipfel PA, et al., Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Curr Biol. 2006 Jan 10;16(1):35-46
• All: 2 reference(s)