Sall4^{Gt(W097E01)Flo}
Gene trapped Allele Detail

Summary

• Symbol: Sall4^{Gt(W097E01)Flo}
• Name: spalt like transcription factor 4; gene trap W097E01, Thomas Floss
• MGI ID: MGI:3613746
• Synonyms: Sall4-1a, Sall4^{Gt(pT1Betageo)1Flo}
• Gene: Sall4 Location: Chr2:168590252-168609121 bp, - strand Genetic Position: Chr2, 88.99 cM
• Alliance: Sall4^{Gt(W097E01)Flo} page

Mutation origin

• Mutant Cell Line: W097E01
• Germline Transmission: Earliest citation of germline transmission: J:138922
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Hypomorph, Reporter)
• Mutation: Insertion of gene trap vector Vector: pT1betageo
• Mutation details: A gene trap vector inserted into intron 1. Low level expression of a 96 kD isoform also present in wild-type cells is detected in homozygous mutant ES cells but expression of the 113 kD isoform is absent. (J:138922)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  W097E01	CL212045 ; (MGI Seq Detail)	5' RACE	Chr13:44885245-44885391 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  177 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	79 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall4 Mutation: 145 strains or lines available

References

• Original: J:138922 Uez N, et al., Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo. Genesis. 2008 Sep 9;46(9):463-477
• All: 3 reference(s)