Osr1^tm1Jian
Targeted Allele Detail

Summary

• Symbol: Osr1^tm1Jian
• Name: odd-skipped related transcription factor 1; targeted mutation 1, Rulang Jiang
• MGI ID: MGI:3613748
• Synonyms: Odd1^-, Odd1^tm1Jian, Odd1^tm1RJ
• Gene: Osr1 Location: Chr12:9624442-9631500 bp, + strand Genetic Position: Chr12, 4.05 cM
• Alliance: Osr1^tm1Jian page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104942
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A targeting construct was designed to insert a lacZ-loxP-neo-loxP cassette into exon 2. The cassette replaces 335 bp of the coding region. The expected protein would contain a functional beta-gal fused to the N-terminal 16 amino acids. X-gal staining detected lacZ activity corresponding to expected activity of the endogenous protein. (J:104942)

Expression

In Mice Carrying this Mutation:	145 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	18 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Osr1 Mutation: 18 strains or lines available

References

• Original: J:104942 Wang Q, et al., Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development. Dev Biol. 2005 Dec 15;288(2):582-94
• All: 14 reference(s)