Ube2i^tm1.1Adej
Targeted Allele Detail

Summary

• Symbol: Ube2i^tm1.1Adej
• Name: ubiquitin-conjugating enzyme E2I; targeted mutation 1.1, Anne Dejean
• MGI ID: MGI:3614394
• Synonyms: Ubc9^inv
• Gene: Ube2i Location: Chr17:25479482-25493856 bp, - strand Genetic Position: Chr17, 12.53 cM
• Alliance: Ube2i^tm1.1Adej page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:104945
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Inversion
• Ube2i^tm1.1Adej involves 1 genes/genome features (Ube2i) View all
• Mutation details: Cre expression resulted in the inversion of exons 2 and 3. Western blot confirm that the allele is null. (J:104945)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ube2i Mutation: 22 strains or lines available

References

• Original: J:104945 Nacerddine K, et al., The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice. Dev Cell. 2005 Dec;9(6):769-79
• All: 2 reference(s)