Muc2^wnn
Chemically induced Allele Detail

Summary

• Symbol: Muc2^wnn
• Name: mucin 2; winnie
• MGI ID: MGI:3614806
• Gene: Muc2 Location: Chr7:141276583-141308428 bp, + strand Genetic Position: Chr7, 87.1 cM, cytoband F5
• Alliance: Muc2^wnn page

Spontaneous colitis in Muc2^wnn/Muc2^wnn mice

Show the 7 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6JSfdAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation was identified in an ENU mutagenesis screen. It constitutes a G-to-A transition at genomic nucleotide position +9414 from the translation initiation site, which replaces cysteine with tyrosine at amino acid position 986 of the protein (C986Y).
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Muc2^wnn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Muc2 Mutation: 82 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 11 reference(s)