Dsc3tm1Pko
Targeted Allele Detail
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| Symbol: |
Dsc3tm1Pko |
| Name: |
desmocollin 3; targeted mutation 1, Peter J Koch |
| MGI ID: |
MGI:3615340 |
| Synonyms: |
Dsc3- |
| Gene: |
Dsc3 Location: Chr18:20093987-20135408 bp, - strand Genetic Position: Chr18, 11.11 cM
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| Alliance: |
Dsc3tm1Pko page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:105239
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| Parent Cell Line: |
W4 (ES Cell)
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| Strain of Origin: |
129S6/SvEvTac
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A floxed PGK-neo cassette replaced part of the promoter, exon 1 (containing the start codon) and intron 1. Quantitative PCR and Western blot analysis demonstrated that expression in heterozygous mice is half that of wild-type mice.
(J:105239)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Dsc3 Mutation: |
49 strains or lines available
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| Original: |
J:105239 Den Z, et al., Desmocollin 3 is required for pre-implantation development of the mouse embryo. J Cell Sci. 2006 Feb 1;119(Pt 3):482-9 |
| All: |
1 reference(s) |
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Analysis Tools
