Mapk13^tm1Cnd
Targeted Allele Detail

Summary

• Symbol: Mapk13^tm1Cnd
• Name: mitogen-activated protein kinase 13; targeted mutation 1, Ana Cuenda
• MGI ID: MGI:3615495
• Synonyms: p38delta^-
• Gene: Mapk13 Location: Chr17:28988260-28997678 bp, + strand Genetic Position: Chr17, 15.0 cM, cytoband A3-B
• Alliance: Mapk13^tm1Cnd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105203
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 4-6 and part of 7 by homologous recombination. Immunoblot failed to detect protein in mutants. (J:105203)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mapk13 Mutation: 26 strains or lines available

References

• Original: J:105203 Sabio G, et al., p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. EMBO J. 2005 Mar 23;24(6):1134-45
• All: 17 reference(s)