Ppard^tm2Rev
Targeted Allele Detail

Summary

• Symbol: Ppard^tm2Rev
• Name: peroxisome proliferator activator receptor delta; targeted mutation 2, Ronald M Evans
• MGI ID: MGI:3616172
• Synonyms: Ppard^tm1.2Rev
• Gene: Ppard Location: Chr17:28451715-28520446 bp, + strand Genetic Position: Chr17, 14.64 cM
• Alliance: Ppard^tm2Rev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105694
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The wild-type exon 4 is replaced with an in-frame lacZ gene upstream of the DNA binding domain. Although no evaluation of beta-galactosidase expression is published, we have been informed that beta-galactosidase expression has not been detected (personal communication). (J:133147)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppard Mutation: 68 strains or lines available

References

• Original: J:105694 Barak Y, Creation of the allele Ppard^tm1.2Rev. MGI Direct Data Submission. 2006
• All: 2 reference(s)