Del(2Hoxd9-Hoxd12)20Ddu
Targeted Allele Detail

Summary

• Symbol: Del(2Hoxd9-Hoxd12)20Ddu
• Name: deletion, Chr 2, Denis Duboule 20
• MGI ID: MGI:3616638
• Synonyms: Del20Ddu, Del(9-12)
• Gene: Del(2Hoxd9-Hoxd12)20Ddu Location: Chr2:74505357-74530552 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105255
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(2Hoxd9-Hoxd12)20Ddu involves 7 genes/genome features (Hoxd12, Hoxd11, Hoxd10 ...) View all
• Mutation details: Produced by targeted meiotic recombination in a cross between Hoxd^tm3Ddu and Hoxd^tm14Ddu in the presence of Tg(Sycp1-cre)4Min. Hoxd9, Hoxd10, Hoxd11, and Hoxd12, are all deleted from the Hoxd cluster. (J:105255)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Hoxd9-Hoxd12)20Ddu Mutation: 0 strains or lines available

References

• Original: J:105255 Tarchini B, et al., Control of Hoxd genes' collinearity during early limb development. Dev Cell. 2006 Jan;10(1):93-103
• All: 8 reference(s)