Tg(Mt1-Ptch1)MT22Mps
Transgene Detail

Summary

• Symbol: Tg(Mt1-Ptch1)MT22Mps
• Name: transgene insertion MT22, Matthew P Scott
• MGI ID: MGI:3617013
• Transgene: Tg(Mt1-Ptch1)MT22Mps Location: unknown
• Alliance: Tg(Mt1-Ptch1)MT22Mps page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mt1-Ptch1)MT22Mps expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ptch1 (MGI:105373)

• Mutation details: A Ptch1 cDNA from which the 5'UTR and 3'UTR were removed was cloned into an expression vector containing the mouse metallothionein I promoter. Two of four lines were maintained. This line has a lower transgene copy number and a milder phenotype than the other. (J:56195)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:56195 Milenkovic L, et al., Mouse patched1 controls body size determination and limb patterning. Development. 1999 Oct;126(20):4431-40
• All: 3 reference(s)