Tdo2^chky
Spontaneous Allele Detail

Summary

• Symbol: Tdo2^chky
• Name: tryptophan 2,3-dioxygenase; chick yellow
• MGI ID: MGI:3617203
• Gene: Tdo2 Location: Chr3:81865719-81883035 bp, - strand Genetic Position: Chr3, 35.97 cM
• Alliance: Tdo2^chky page

Pale yellow coat and cataracts in the Tdo2^chky/Tdo2^chky Tyr^c/Tyr^c mouse

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: Swiss

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Whole exome sequencing of this spontaneous mutation shows it to be a C-to-T transition in the coding sequence in exon 9, which is a nonsense mutation predicted to result in a premature stop codon at arginine codon 282 (p.R282*). (J:181237, J:222308)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tdo2 Mutation: 38 strains or lines available

References

• Original: J:149273 Karst SY, et al., Chick yellow: Mutation on Chromosome 3 causing eye and coat color abnormalties. MGI Direct Data Submission. 2009
• All: 3 reference(s)