Tg(Nr5a1-cre)7Lowl
Transgene Detail

Summary

• Symbol: Tg(Nr5a1-cre)7Lowl
• Name: transgene insertion 7, Bradford B Lowell
• MGI ID: MGI:3617315
• Synonyms: Line S7, Sf1-cre, SF1^Cre
• Transgene: Tg(Nr5a1-cre)7Lowl Location: unknown
• Alliance: Tg(Nr5a1-cre)7Lowl page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Nr5a1-cre)7Lowl expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Nr5a1

• This transgene includes cre recombinase under the control of Nr5a1 regulatory sequences. (J:105327)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nr5a1 (species not specified) Summary of all recombinase alleles driven by Nr5a1. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

82 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:105327 Dhillon H, et al., Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron. 2006 Jan 19;49(2):191-203
• All: 47 reference(s)