Sema3b^tm1Cast
Targeted Allele Detail

Summary

• Symbol: Sema3b^tm1Cast
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; targeted mutation 1, Valerie Castellani
• MGI ID: MGI:3617382
• Synonyms: Sema3b^-
• Gene: Sema3b Location: Chr9:107474873-107486428 bp, - strand Genetic Position: Chr9, 58.31 cM
• Alliance: Sema3b^tm1Cast page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105299
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The sequence was replaced with a lacZ cassette. (J:105299)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema3b Mutation: 31 strains or lines available

References

• Original: J:105299 Falk J, et al., Dual functional activity of semaphorin 3B is required for positioning the anterior commissure. Neuron. 2005 Oct 6;48(1):63-75
• All: 7 reference(s)