Slc17a7^tm1Edw
Targeted Allele Detail

Summary

• Symbol: Slc17a7^tm1Edw
• Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7; targeted mutation 1, Robert H Edwards
• MGI ID: MGI:3617803
• Synonyms: VGLUT1^-
• Gene: Slc17a7 Location: Chr7:44813373-44825566 bp, + strand Genetic Position: Chr7, 29.16 cM
• Alliance: Slc17a7^tm1Edw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105647
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 and part of 4, encompassing the first two transmembrane domains, were removed via homologous recombination. (J:105647)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc17a7 Mutation: 40 strains or lines available

References

• Original: J:105647 Fremeau RT Jr, et al., Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites. Science. 2004 Jun 18;304(5678):1815-9
• All: 17 reference(s)