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Tg(Ins2-E3*734)3Dvs
Transgene Detail
Summary
Symbol: Tg(Ins2-E3*734)3Dvs
Name: transgene insertion 3, David V Serreze
MGI ID: MGI:3618341
Synonyms: DL734, RIP-DL734, Tg(RIP-E3-734)3Dvs
Transgene: Tg(Ins2-E3*734)3Dvs  Location: unknown  
Alliance: Tg(Ins2-E3*734)3Dvs page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe rat insulin promoter was placed upstream of the adenovirus early reagion 3 (E3) sequences with two point mutations in the first two methionines of the 11.6K open reading frame and this construct was injected into NOD/LtDvs oocytes (J:106340)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:106340 Pierce MA, et al., Adenovirus early region 3 transgenes expressed in beta cells prevent autoimmune diabetes in nonobese diabetic mice: effects of deleting the adenovirus death protein 11.6K. J Virol. 2005 Jan;79(1):619-21
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory