B4galnt2^tm1Jbl
Targeted Allele Detail

Summary

• Symbol: B4galnt2^tm1Jbl
• Name: beta-1,4-N-acetyl-galactosaminyl transferase 2; targeted mutation 1, John B Lowe
• MGI ID: MGI:3618460
• Gene: B4galnt2 Location: Chr11:95756769-95805717 bp, - strand Genetic Position: Chr11, 59.02 cM
• Alliance: B4galnt2^tm1Jbl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:52069
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 8 and 9 were replaced by a neomycin selection cassette. Further details are unpublished.

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B4galnt2 Mutation: 27 strains or lines available

References

• Original: J:52069 Mohlke KL, et al., Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell. 1999 Jan 8;96(1):111-20
• All: 10 reference(s)