Aifm2^tm1Hbsh
Targeted Allele Detail

Summary

• Symbol: Aifm2^tm1Hbsh
• Name: apoptosis-inducing factor, mitochondrion-associated 2; targeted mutation 1, H B Shu
• MGI ID: MGI:3619528
• Synonyms: AMID^-
• Gene: Aifm2 Location: Chr10:61551042-61575039 bp, + strand Genetic Position: Chr10, 32.27 cM
• Alliance: Aifm2^tm1Hbsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105660
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance gene replaced part of exon 2 containing the start codon. Protein was not detected in testis, kidney or spleen of mutant mice. (J:105660)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aifm2 Mutation: 20 strains or lines available

References

• Original: J:105660 Mei J, et al., The p53-inducible apoptotic protein AMID is not required for normal development and tumor suppression. Oncogene. 2006 Feb 9;25(6):849-56
• All: 1 reference(s)