Neil1^tm1Rsld
Targeted Allele Detail

Summary

• Symbol: Neil1^tm1Rsld
• Name: nei endonuclease VIII-like 1 (E. coli); targeted mutation 1, R Stephen Lloyd
• MGI ID: MGI:3620011
• Synonyms: neil1^-
• Gene: Neil1 Location: Chr9:57050084-57055589 bp, - strand Genetic Position: Chr9, 30.89 cM, cytoband C
• Alliance: Neil1^tm1Rsld page

Neil1^tm1Rsld/Neil1^tm1Rsld and wild-type mouse comparison

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106077
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• A PGK-neo cassette was inserted into the coding region contained within exons 2 and 3. (J:106077)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Neil1 Mutation: 18 strains or lines available

References

• Original: J:106077 Vartanian V, et al., The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1864-9
• All: 11 reference(s)