Ads2^NZB
QTL Variant Detail

Summary

• QTL variant: Ads2^NZB
• Name: anti dsDNA antibody 2; NZB
• MGI ID: MGI:3620169
• QTL: Ads2 Location: unknown

Variant origin

• Strain of Specimen: NZB

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased production of IgM anti-dsDNA autoantibodies compared to NZW. (J:7111)
• Inheritance: Dominant

References

• Original: J:7111 Hirose S, et al., Enhancing effect of H-2-linked NZW gene(s) on the autoimmune traits of (NZB X NZW)F1 mice. J Exp Med. 1983 Jul 1;158(1):228-33
• All: 1 reference(s)