Rr149356tm1Che
Targeted Allele Detail
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Symbol: |
Rr149356tm1Che |
Name: |
regulatory region 149356; targeted mutation 1, Jianzhu Chen |
MGI ID: |
MGI:3620665 |
Synonyms: |
EbetaR |
Gene: |
Rr149356 Location: Chr6:41526801-41532817 bp, . strand Genetic Position: Chr6, Syntenic
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Alliance: |
Rr149356tm1Che page
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Germline Transmission: |
Earliest citation of germline transmission:
J:107306
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A concatamer of 8 copies of the Lgals4 binding sequence replaced 560 bp of the locus to inactivate the enhancer and to allow opportunitites to target heterologous proteins to the locus. A floxed neo cassette included in the vector was deleted by cre-mediated excision.
(J:107306)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr149356 Mutation: |
0 strains or lines available
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Original: |
J:107306 Ryu CJ, et al., The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombination. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13465-70 |
All: |
3 reference(s) |
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