Bmp2^tm1.1Jfm
Targeted Allele Detail

Summary

• Symbol: Bmp2^tm1.1Jfm
• Name: bone morphogenetic protein 2; targeted mutation 1.1, James F Martin
• MGI ID: MGI:3620971
• Synonyms: Bmp2^null
• Gene: Bmp2 Location: Chr2:133394079-133404805 bp, + strand Genetic Position: Chr2, 65.21 cM
• Alliance: Bmp2^tm1.1Jfm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99582
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele is a derivative of Bmp2^tm1Jfm in which exon 3 is deleted by Cre-mediated recombination. Mice carrying the Bmp2^tm1Jfm allele were mated to Tg(Nes-cre)1Mrt mice (J:58999) and offspring were screened for the heritable deletion. PCR analysis confirmed deletion of exon 3. (J:99582)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp2 Mutation: 27 strains or lines available

References

• Original: J:99582 Ma L, et al., Generation of a Bmp2 conditional null allele. Genesis. 2005 Jul;42(3):203-6
• All: 3 reference(s)