Tg(MMTV-Myc)#Led
Transgene Detail

Summary

• Symbol: Tg(MMTV-Myc)#Led
• Name: transgene insertion, Philip Leder
• MGI ID: MGI:3621200
• Synonyms: MMTVmyc, MTV/myc, Tg(MMTV-Myc)Led
• Transgene: Tg(MMTV-Myc)#Led Location: unknown
• Alliance: Tg(MMTV-Myc)#Led page

Transgene origin

• Strain of Origin: (CD-1 x C57BL/6J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Myc)#Led expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myc (MGI:97250)

• Mutation details: This transgene contains the MMTV (mouse mammary tumor virus) promoter and the mouse Myc (myelocytomatosis) oncogene. Multiple founders were generated, this allele represents citations without an identifiable founder or citations using pooled cohorts. (J:29013)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-Myc)#Led

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Several lines were generated using four different constructs: MTV-H3 myc construct (lines 139-1, 141-3, 143-3, 143-5) MTV-Sma myc construct (lines 147-6, 147-9a, 147-9b) MTV-Stu myc construct (lines 155-2, 155-7) MTV-Xba myc construct (lines 164-4a, 164-4b, 165-1a, 165-1b)

References

• Original: J:29013 Stewart TA, et al., Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes. Cell. 1984 Oct;38(3):627-37
• All: 13 reference(s)