Postn^tm1Kudo
Targeted Allele Detail

Summary

• Symbol: Postn^tm1Kudo
• Name: periostin, osteoblast specific factor; targeted mutation 1, Akira Kudo
• MGI ID: MGI:3621456
• Synonyms: periostin^-, PN^-, Postn^tm2Kudo
• Gene: Postn Location: Chr3:54268530-54298458 bp, + strand Genetic Position: Chr3, 25.46 cM
• Alliance: Postn^tm1Kudo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131434
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

Allele Type: Targeted (Null/knockout) Mutation: Insertion Mutation details: A neomycin resistance gene was inserted into the locus. The neo was subsequently removed by cre mediated recombination. (J:106783, J:131434)

Generation of the Postn^tm1Kudo allele

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Postn Mutation: 53 strains or lines available

References

• Original: J:131434 Shimazaki M, et al., Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med. 2008 Feb 18;205(2):295-303
• All: 18 reference(s)