Dner^tm1Hta
Targeted Allele Detail

Summary

• Symbol: Dner^tm1Hta
• Name: delta/notch-like EGF repeat containing; targeted mutation 1, Hiroshi Takeshima
• MGI ID: MGI:3621906
• Synonyms: Dner^-
• Gene: Dner Location: Chr1:84347560-84673942 bp, - strand Genetic Position: Chr1, 43.4 cM
• Alliance: Dner^tm1Hta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106886
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neomycin resistance gene. Western blot failed to detect protein in mutants. (J:106886)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dner Mutation: 52 strains or lines available

References

• Original: J:106886 Tohgo A, et al., Impaired cerebellar functions in mutant mice lacking DNER. Mol Cell Neurosci. 2006 Feb;31(2):326-33
• All: 3 reference(s)