Musk^tm1.1Vwi
Targeted Allele Detail

Summary

• Symbol: Musk^tm1.1Vwi
• Name: muscle, skeletal, receptor tyrosine kinase; targeted mutation 1.1, Veit Witzemann
• MGI ID: MGI:3621908
• Synonyms: MuSK^-
• Gene: Musk Location: Chr4:58285962-58374303 bp, + strand Genetic Position: Chr4, 31.87 cM
• Alliance: Musk^tm1.1Vwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:106867
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The kinase domain was deleted via cre mediated recombination. (J:106867)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Musk Mutation: 42 strains or lines available

References

• Original: J:106867 Hesser BA, et al., Synapse disassembly and formation of new synapses in postnatal muscle upon conditional inactivation of MuSK. Mol Cell Neurosci. 2006 Mar;31(3):470-80
• All: 2 reference(s)