Usp14^nmf375
Chemically induced Allele Detail

Summary

• Symbol: Usp14^nmf375
• Name: ubiquitin specific peptidase 14; neuroscience mutagenesis facility, 375
• MGI ID: MGI:3622127
• Synonyms: NMF375
• Gene: Usp14 Location: Chr18:9993615-10030149 bp, - strand Genetic Position: Chr18, 4.91 cM
• Alliance: Usp14^nmf375 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transition in position 4 of the splice site donor region of intron 9. Western blot anlaysis confirmed the absence of protein expression in the spinal cord without the detection of truncated proteins. Authors state that this allele is hypomorphic based on phenotypic analysis.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Usp14 Mutation: 47 strains or lines available

References

• Original: J:87349 JAX Neuroscience Mutagenesis Facility, Heritable mouse mutants from JAX NMF ENU Mutagenesis Program. MGI Direct Data Submission. 2004-7
• All: 2 reference(s)