Stra8^tm1Dcp
Targeted Allele Detail

Summary

• Symbol: Stra8^tm1Dcp
• Name: stimulated by retinoic acid gene 8; targeted mutation 1, David C Page
• MGI ID: MGI:3622304
• Synonyms: Stra8^-
• Gene: Stra8 Location: Chr6:34897098-34916279 bp, + strand Genetic Position: Chr6, 15.2 cM
• Alliance: Stra8^tm1Dcp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:107319
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An IRES-lacZ-neocassette was inserted into exon 2, replacing exons 3-6 and part of exon 7. (J:116498)

Expression

In Mice Carrying this Mutation:

9 assay results 3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Stra8 Mutation: 36 strains or lines available

References

• Original: J:107319 Koubova J, et al., Retinoic acid regulates sex-specific timing of meiotic initiation in mice. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2474-9
• All: 16 reference(s)